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  1. Research article

    Comparative study of sickle cell anemia and hemoglobin SC disease: clinical characterization, laboratory biomarkers and genetic profiles

    In this study, we evaluate the association of different clinical profiles, laboratory and genetic biomarkers in patients with sickle cell anemia (SCA) and hemoglobin SC disease (HbSC) in attempt to characteriz...

    Milena Magalhães Aleluia, Teresa Cristina Cardoso Fonseca, Regiana Quinto Souza, Fábia Idalina Neves, Caroline Conceição da Guarda, Rayra Pereira Santiago, Bruna Laís Almeida Cunha, Camylla Villas Boas Figueiredo, Sânzio Silva Santana, Silvana Sousa da Paz, Júnia Raquel Dutra Ferreira, Bruno Antônio Veloso Cerqueira and Marilda de Souza Gonçalves

    BMC Hematology 2017 17:15

    Published on: 15 September 2017

  2. Research article

    Alterations in hematologic indices during long-duration spaceflight

    Although a state of anemia is perceived to be associated with spaceflight, to date a peripheral blood hematologic assessment of red blood cell (RBC) indices has not been performed during long-duration space mi...

    Hawley Kunz, Heather Quiriarte, Richard J. Simpson, Robert Ploutz-Snyder, Kathleen McMonigal, Clarence Sams and Brian Crucian

    BMC Hematology 2017 17:12

    Published on: 8 September 2017

  3. Research article

    An outline of anemia among adolescent girls in Bangladesh: findings from a cross-sectional study

    Anemia is a significant wide spread public health threat especially among the adolescent girls who are more vulnerable towards low level of hemoglobin particularly of low and middle income countries (LMICs). W...

    Sabuj Kanti Mistry, Fatema Tuz Jhohura, Fouzia Khanam, Fahmida Akter, Safayet Khan, Fakir Md Yunus, Md Belal Hossain, Kaosar Afsana, Md Raisul Haque and Mahfuzar Rahman

    BMC Hematology 2017 17:13

    Published on: 22 August 2017

  4. Research article

    Diagnostic utility of zinc protoporphyrin to detect iron deficiency in Kenyan preschool children: a community-based survey

    Zinc protoporphyrin (ZPP) has been used to screen and manage iron deficiency in individual children, but it has also been recommended to assess population iron status. The diagnostic utility of ZPP used in com...

    Emily M. Teshome, Andrew M. Prentice, Ayşe Y. Demir, Pauline E.A. Andang’o and Hans Verhoef

    BMC Hematology 2017 17:11

    Published on: 27 July 2017

  5. Research article

    Prevalence of Anaemia and Associated Risk Factors among Children in North-western Uganda: A Cross Sectional Study

    Despite the public health significance of anaemia in African children, its broader and often preventable risk factors remain largely under described. This study investigated, for the first time, the prevalence...

    Ismail Dragon Legason, Alex Atiku, Ronald Ssenyonga, Peter Olupot-Olupot and John Banson Barugahare

    BMC Hematology 2017 17:10

    Published on: 3 July 2017

  6. Research article

    Circumcision in hemophilia using low quantity of factor concentrates: experience from Dakar, Senegal

    Circumcision in hemophiliacs is a delicate surgery because of bleeding risks that could be avoided by adequate substitution of coagulation factor. This practice is very challenging in countries where anti hemo...

    Moussa Seck, Aloïse Sagna, Mame Sokhna Guéye, Blaise Félix Faye, Diariétou Sy, Sokhna Aissatou Touré, Abibatou Sall, Awa Oumar Touré and Saliou Diop

    BMC Hematology 2017 17:8

    Published on: 24 April 2017

  7. Research article

    Prevention practices influencing frequency of occurrence of vaso-occlusive crisis among sickle cell patients in Abeokuta South Local Government Area of Ogun State, Nigeria

    Africa is the most affected continent with 200,000 new born affected by sickle cell anemia annually with of 5% of under five deaths. Nigeria has the largest sickle cell gene pool in the world with about 2% of ...

    Olorunfemi Emmanuel Amoran, Ahmed Babatunde Jimoh, Omotola Ojo and Temitope Kuponiyi

    BMC Hematology 2017 17:6

    Published on: 20 April 2017

  8. Research article

    Chronic complications and quality of life of patients living with sickle cell disease and receiving care in three hospitals in Cameroon: a cross-sectional study

    Sickle Cell Disease (SCD) is associated with chronic multisystem complications that significantly influence the quality of life (QOL) of patients early in their life. Although sub-Saharan Africa bears 75% of t...

    Anne M. Andong, Eveline D. T. Ngouadjeu, Cavin E. Bekolo, Vincent S. Verla, Daniel Nebongo, Yannick Mboue-Djieka and Simeon-Pierre Choukem

    BMC Hematology 2017 17:7

    Published on: 20 April 2017

  9. Case report

    Case report: primary osteonecrosis associated with thrombophilia-hypofibrinolysis and worsened by testosterone therapy

    Familial and acquired thrombophilia are often etiologic for idiopathic hip and jaw osteonecrosis (ON), and testosterone therapy (TT) can interact with thrombophilia, worsening ON.

    Michael Ian Jarman, Kevin Lee, Ariel Kanevsky, Sarah Min, Ilana Schlam, Chris Mahida, Ali Huda, Alexander Milgrom, Naila Goldenberg, Charles J. Glueck and Ping Wang

    BMC Hematology 2017 17:5

    Published on: 27 March 2017

  10. Research article

    Gum Arabic as novel anti-oxidant agent in sickle cell anemia, phase II trial

    Sickle cell anemia patients suffer from oxidative stress due to chronic inflammation and self-oxidation of sickle hemoglobin (Hb S). Chronic oxidative stress contributes to endothelial dysfunction, inflammatio...

    Lamis Kaddam, Imad Fadl-Elmula, Omer Ali Eisawi, Haydar Awad Abdelrazig, Mohammed Abdelraman Salih, Florian Lang and Amal M. Saeed

    BMC Hematology 2017 17:4

    Published on: 16 March 2017

  11. Case report

    Chronic lymphocytic leukemia with clinical debut as neurological involvement: a rare phenomenon and the need for better predictive markers

    Chronic lymphocytic leukemia (CLL) is the most common leukemia in Western countries. The frequency of symptomatic central nervous system (CNS) involvement is unknown but thought to be a rare phenomenon. Curren...

    Cristhiam M. Rojas-Hernandez, Jacklyn Nemunaitis, Kristopher D. Marjon, Daniel Bustamante, Qian-Yun Zhang and Jennifer M. Gillette

    BMC Hematology 2017 17:3

    Published on: 2 February 2017

  12. Research article

    Sickle-cell disease in febrile children living in a rural village of Madagascar and association with malaria and respiratory infections

    In Madagascar, the last study on sickle cell disease (SCD) was done in the early 1980s. The country is known as endemic for malaria and respiratory infections. The main objective of this study was to estimate ...

    Muriel N. Maeder, Henintsoa M. Rabezanahary, Norosoa J. Zafindraibe, Martin Raoelina Randriatiana, Tahinamandranto Rasamoelina, Andry T. Rakotoarivo, Philippe Vanhems, Jonathan Hoffmann, Thomas Bénet, Mala Rakoto Andrianarivelo and Olivat A. Rakoto-Alson

    BMC Hematology 2016 16:30

    Published on: 1 December 2016

  13. Case report

    Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma

    Hemophagocytic lymphohistiocytosis in adults is often secundary to an infection or a neoplasm. In this last case, T cell lymphomas are the most frequent causes. Hemophagocytic lymphohistiocytosis secundary to ...

    El Mehdi Mahtat, Maryem Zine, Mohamed Allaoui, Malika Kerbout, Nezha Messaoudi, Kamal Doghmi and Mohamed Mikdame

    BMC Hematology 2016 16:28

    Published on: 24 November 2016

  14. Research article

    Prevalence of transfusion transmissible infections in blood donors of Pakistan

    Transfusion-transmitted infections threaten the safety of patients requiring blood transfusion, which in turn imposes serious challenges for the availability of safe blood products that are still affordable in...

    Aisha Arshad, Munira Borhany, Nida Anwar, Imran Naseer, Rehan Ansari, Samson Boota, Naveena Fatima, Mustansir Zaidi and Tahir Shamsi

    BMC Hematology 2016 16:27

    Published on: 18 November 2016

  15. Research article

    Adherence to treatment regimen and bleeding rates in a prospective cohort of youth and young adults on low-dose daily prophylaxis for severe hemophilia A

    When availability and/or affordability of anti-hemophilic factor concentrates are limited, optimal prophylaxis regimens in severe hemophilia A (HA) remain to be determined. In selected situations, low-dose dai...

    Terry Mizrahi, Jean St-Louis, Nancy L. Young, Francine Ménard, Nichan Zourikian, Evemie Dubé and Georges E. Rivard

    BMC Hematology 2016 16:26

    Published on: 8 November 2016

  16. Research article

    KIR repertory in patients with hematopoietic diseases and healthy family members

    Since the discovery of specific histocompatibility, literature has associated genes involved in the immune response, like the Human Leucocyte Antigen (HLA), with a better prognosis in transplantation. However,...

    Daniele Kazue Sugioka, Carlos Eduardo Ibaldo Gonçalves and Maria da Graça Bicalho

    BMC Hematology 2016 16:25

    Published on: 29 September 2016

  17. Study protocol

    Anticoagulated patient’s perception of their illness, their beliefs about the anticoagulant therapy prescribed and the relationship with adherence: impact of novel oral anticoagulant therapy – study protocol for The Switching Study: a prospective cohort study

    Anticoagulant therapy is prescribed for millions of patients worldwide for the prevention and treatment of both arterial and venous thrombosis. Historically, only vitamin K antagonists have been available for ...

    Vivian Auyeung, Jignesh P. Patel, John K. Abdou, Bipin Vadher, Lynda Bonner, Alison Brown, Lara N. Roberts, Raj K. Patel and Roopen Arya

    BMC Hematology 2016 16:22

    Published on: 23 August 2016

  18. Study protocol

    A randomized controlled trial studying the effectiveness of group medical appointments on self-efficacy and adherence in sickle cell disease (TEAM study): study protocol

    Sickle cell disease (SCD) is endemic in non-Western countries. Due to migration, the prevalence of SCD in the Netherlands has increased. Adherence to medical treatment is recognized as a major problem area. Th...

    Marlous J. Madderom, Jessica Heijdra, Elisabeth M. W. J. Utens, Suzanne Polinder, Anita W. Rijneveld and Marjon H. Cnossen

    BMC Hematology 2016 16:21

    Published on: 4 August 2016

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