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Table 1 Etiological breakup of 250 cases of pancytopenia

From: An etiological reappraisal of pancytopenia - largest series reported to date from a single tertiary care teaching hospital

Causes

No. of cases

Hypersplenism

 

Congestive splenomegaly

45

Malaria

15

Tropical splenomegaly

3

Thalassemia

1

Hodgkin’s Disease

1

Idiopathic

8

Total

73 (29.2% )

Infections

 

AIDS

30

Septicemia

14

Enteric fever

9

Tuberculosis

8

Viral hepatitis

3

Total

64 (25.6% )

Myelosuppressants

 

Carcinoma

18

Leukemia

7

Non-Hodgkin’s lymphoma (NHL)

5

Hodgkin’s disease

2

Others

10

Total

42 (16.8% )

Megaloblastosis

33 (13.2%)

Hypoplastic / Aplastic anemia

12 (4.8%)

Leukemia

7 (2.8%)

Lymphoma

2 (0.8%)

Plasma cell dyscrasia (PCD)

2 (0.8%)

Myelodysplastic syndrome (MDS)

1 (0.4%)

Miscellaneous

14 (5.6%)

Grand Total

250 (100%)