Figure 1From: The IL-10 polarized cytokine pattern in innate and adaptive immunity cells contribute to the development of FVIII inhibitorsAnalysis of intracytoplasmic cytokine profile of monocytes and neutrophils from the peripheral blood of blood donors (BDs; white bars), patients with HA who are negative for anti-FVIII inhibitors (HAα-FVIII[−]; light gray bars), and patients with HA who are positive for anti-FVIII inhibitors (HAα-FVIII[+]; dark gray bars). Statistical significance at p < 0.05 is represented by letters “a”, “b”, and “c” for comparisons with BDs, HAα-FVIII(−) patients, and HAα-FVIII(+) patients, respectively. The number of gated neutrophils and monocytes ranged from 19,500 to 22,500 and from 1,200 to 2,100, respectively.Back to article page